Clinical / Major Depression

Clinical / Major Depression Awareness, Research and Resources

“Understanding the difference between healthy striving and perfectionism is critical to laying down the shield and picking up your life. Research shows that perfectionism hampers success. In fact, it’s often the path to depression, anxiety, addiction, and life paralysis.” ― Brené Brown

Clinical Depression / Major Depression Research

Clinical / Major Depression

Major depressive disorder (MDD), also known as clinical depression or major depression, is a mental health condition characterized by persistent feelings of sadness, low mood, or a loss of interest or pleasure in activities. It goes beyond normal fluctuations in mood and can significantly impact a person's daily functioning, relationships, and overall well-being.

Here are some key features and symptoms associated with major depression:

1. Persistent Depressed Mood: A person with major depression experiences a depressed mood most of the day, nearly every day. This can manifest as feelings of sadness, emptiness, or hopelessness.

2. Loss of Interest or Pleasure: A diminished interest or pleasure in most activities, including those previously enjoyed, is a common symptom. Hobbies, social interactions, and even basic daily activities may lose their appeal.

3. Significant Weight Change: A noticeable weight loss or gain without intentional changes in diet or exercise may occur in individuals with depression.

4. Sleep Disturbances: Insomnia (difficulty falling asleep, staying asleep, or early morning awakening) or hypersomnia (excessive sleepiness) can be symptoms of major depression.

5. Fatigue or Loss of Energy: Feeling tired, lacking energy, or experiencing a general sense of physical and mental sluggishness is often reported by those with depression.

6. Feelings of Worthlessness or Guilt: Individuals with major depression often feel excessively guilty or worthless, even in the absence of logical reasons.

7. Difficulty Concentrating or Making Decisions: Depression can impair cognitive abilities, making it challenging to focus, think clearly, or make decisions.

8. Recurrent Thoughts of Death or Suicidal Ideation: Some people with major depression have recurrent thoughts of death or suicide. It's crucial to take these thoughts seriously and seek help if you or someone you know is experiencing them.

To diagnose major depression, mental health professionals typically use the criteria outlined in the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), published by the American Psychiatric Association.

Treatment for major depression often involves a combination of psychotherapy (such as cognitive-behavioral therapy or interpersonal therapy) and medication, such as selective serotonin reuptake inhibitors (SSRIs) or other antidepressants. Lifestyle modifications, such as regular exercise, a balanced diet, and sufficient sleep, can also support the treatment process.

If you or someone you know is experiencing symptoms of major depression, it's essential to seek help from a qualified mental health professional. They can provide an accurate diagnosis and develop an individualized treatment plan to address the condition effectively." (Source: ChatGPT 2023)

Clinical / Major Depression Online Resources

APA Clinical Practice Guideline for the Treatment of Depression Across Three Age Cohorts PDF Download  APA American Psychological Association

Barriers to complete recovery of major depression: Cross-sectional, multi-centre study on clinical practice. RECORD study Elsevier

Best Depression Resources and Organizations for Support and Treatment Verywell Mind

Clinical Depression and Empathy Mental Health and Motivation

Clinical Depression: Symptoms, Diagnosis, Treatment Verywell Mind

Clinical Depression: What does that mean? Mayo Clinic

Clinical Practice Review for Major Depressive Disorder Anxiety & Depression Association of America

Depression: Resources and References camh

Depression (Major Depressive Disorder) Clinical Trials Mayo Clinic

Depression Clinical Trials at UCSF University of California San Francisco

Depression Clinical & Research Program Massachusetts General Hospital

Depression News ScienceDaily

Depression Resources American Counceling Association

Depressive Disorder (Depression) Fact Sheet WHO / World Health Organization 

Depression Treatment Options for Adults (Beyond the Basics) UpToDate

Depression: Types, Symptoms, Causes & Treatment Cleveland Clinic

Depression Research Clinic Stanford Medicine

Depression Signs, Symptoms, Latest Treatments, Tests, and More Everyday Health

Frequently Asked Questions about Depression Brain & Behavior Research Foundation

Helpful Online Resources for Depression WebMD

Helpful Websites for Managing Major Depressive Disorder Fetzima

Major Depressive Disorder: Advances in Neuroscience Research and Translational Applications Springer Link

Major Depression | Mental Health in Children Cincinnati Children's

Newly Discovered Trigger for Major Depression Opens New Possibilities for Treatments Neuroscience News

Prognosis and Improved Outcomes in Major Depression: A Review Psychiatry Online

Resources for Clinicians for the Treatment of Depression in Adults American Psychological Association

Self-Help Methods for Major Depression MentalHelp

Single-Dose Psilocybin for a Treatment-Resistant Episode of Major Depression The New England Journal of Medicine

The Right Resources Can Help You Manage Depression Everyday Health

The Serotonin Theory of Depression: A Systematic umbrella Review of the Evidence Molecular Psychiatry

Three Phases of Treatment of Major Depression PCORE

Treating depression in young people Guidance, resources and tools for assessment and management PDF Download Orygen

Top 5 Mental Health Challenges Facing College Students and How to Get Help Best Colleges

Types of Depression Beyond Blue

Understanding and Finding Help for Depression Canadian Mental Health Organization

What Causes Depression? Harvard Health Publishing

What is Major Depression? WebMD

Clinical / Major Depression Books

Beating Depression: The Complete Guide to Depression and How to Overcome It
Stefan Cembroxicz / Dorcas Kingham

Depression Self Help : How to Deal with Depression, Overcome Depression and Symptoms and Signs of Depression Isabel Jones

Handbook of Depression and Anxiety: A Biological Approach, Second Edition
(Medical Psychiatry, 21) Siegfried Kasper / Johan A. den Boer / J.M. Ad Sitsen

Holistic Solutions for Anxiety & Depression in Therapy
Peter Bongiorno

What is Depression? - Video

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